LIFE EXTENSION I Dovolj vitamina C bi lahko pomagalo zaustaviti levkemijo

Tags

vitamin c lifeextension levkemija

Članek, objavljen 21. avgusta 2017 v Nature, opisuje raziskave, ki se izvajajo na Otroškem raziskovalnem inštitutu Southwestern Medical Research Centre (Southwestern Children's Research Institute, Southwestern Medical Center, ZDA), v katerih so ugotovili, da hematopoetske (krvotvorne) matične celice potrebujejo in privzemajo visoko koncentracijo vitamina C, ki ureja njihovo delovanje in zavira razvoj levkemije.

"Matične celice uporabljajo askorbat za uravnavanje mnogih kemičnih modifikacij na DNA, ki so del epigenoma," je pojasnil vodilni avtor Michalis Agathocleous. "Epigenom je sklop mehanizmov znotraj celice, ki uravnava, kateri geni se vklopijo in izklopijo."

Avtorji so ugotovili, da vitamin C uravnava funkcijo hematopoetskih matičnih celic deloma prek mehanizmov, ki vključujejo encim Tet2, ki je, kadar je mutiran, inaktiviran že zgodaj v razvoju levkemije. "Ena najpogostejših mutacij pri bolnikih s klonalno hematopoezo je izguba ene kopije Tet2". Rezultati kažejo na to, da morajo biti bolniki s klonalno hematopoezo in mutacijo Tet2 še posebej previdni, da zaužijejo 100 % dnevne količine vitamina C. Ker imajo ti bolniki le eno dobro kopijo Tet2, morajo maksimirati preostalo Tet2-tumorsko supresorsko aktivnost, da se zaščitijo pred rakom. "

"Dolgo časa smo vedeli, da imajo ljudje z nižjimi vrednostmi askorbata (vitamina C) večje tveganje za raka, vendar nismo v celoti razumeli, zakaj."Rezultati novih študij dajejo del razlage, vsaj za krvotvorni sistem. "

Name	Description
PHPSESSID	Preserves the visitor's session state across page requests.
bioep_shown
bioep_shown_session
cpp_count
form_key	Protects visitor's data from Cross-Site Request Forgery Attacks.
guest-view	Stores the Order ID that guest shoppers use to retrieve their order status. Used in “Orders and Returns” widgets.
guest_customer_id
login_redirect	Preserves the destination page the customer was loading before being directed to log in.
mage-banners-cache-storage	Stores banner content locally to improve performance.
mage-cache-sessid	The value of this cookie triggers the cleanup of local cache storage.
mage-cache-storage	Local storage of visitor-specific content that enables ecommerce functions.
mage-cache-storage-section-invalidation	Forces local storage of specific content sections that should be invalidated.
mage-messages	Tracks error messages and other notifications that are shown to the user, such as the cookie consent message, and various error messages. The message is deleted from the cookie after it is shown to the shopper.
private_content_version	Appends a random, unique number and time to pages with customer content to prevent them from being cached on the server.
section_data_clean
section_data_ids	Stores customer-specific information related to shopper-initiated actions such as display wish list, checkout information, etc.
user_allowed_save_cookie, cookie_consent	Stores the user's cookie consent state for the current domain.
X-Magento-Vary	Configuration setting that improves performance when using Varnish static content caching.

Name	Description
product_data_storage	Stores configuration for product data related to Recently Viewed / Compared Products.
recently_compared_product	Stores product IDs of recently compared products.
recently_compared_product_previous	Stores product IDs of previously compared products for easy navigation.
recently_viewed_product	Stores product IDs of recently viewed products for easy navigation.
recently_viewed_product_previous	Stores product IDs of recently previously viewed products for easy navigation.
_fbp	This cookie is installed by Facebook to store and track visits across websites.

Name	Description
add_to_cart, remove_from_cart	Used by Google Tag Manager. Captures the product SKU, name, price and quantity added or removed from the cart, and makes the information available for future integration by third-party scripts.
dc_gtm_*	Throttles request rate when Google Analytics is deployed with Google Tag Manager.
_ga, _gat, _gid, _ga_, _gat_	This cookie is installed by Google Analytics. They are used to collect information about how visitors use our website. We use the information to compile reports and to help us improve the website. The cookies collect information in a way that does not directly identify anyone.

Dovolj vitamina C bi lahko pomagalo zaustaviti levkemijo

Our use of cookies